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Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma

✍ Scribed by Scott M. Schuetze; Lili Zhao; Rashmi Chugh; Dafydd G. Thomas; David R. Lucas; Gino Metko; Mark M. Zalupski; Laurence H. Baker

Book ID
116431106
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
275 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract ## BACKGROUND The authors conducted a 2‐arm Phase II trial of 9‐nitrocamptothecin (9‐NC), an oral topoisomerase I inhibitor, to define response rates in patients with gastrointestinal (GI) leiomyosarcomas and other soft‐tissue sarcomas (STS). ## METHODS Patients were required to prov