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Restriction of hexobarbital metabolism by t-butyl hydroperoxide in perfused rat liver

✍ Scribed by C. Gerstenecker; H. Sies


Book ID
115775308
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
298 KB
Volume
29
Category
Article
ISSN
0006-2952

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## Abstract The hepatotoxic and lipid peroxidative potentials of __t__‐butyl hydroperoxide (__t__‐BuOOH) towards isolated perfused rat livers were investigated at doses of 1 and 3 mmol I^βˆ’1^. __t__‐BuOOH led to a concentration‐dependent release of cytosolic (glutamate‐pyruvate transaminase and lact