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Restoration of Diastolic Function in Senescent Rat Hearts Through Adenoviral Gene Transfer of Sarcoplasmic Reticulum Ca2+-ATPase

✍ Scribed by Schmidt, U.; del Monte, F.; Miyamoto, M. I.; Matsui, T.; Gwathmey, J. K.; Rosenzweig, A.; Hajjar, R. J.


Book ID
121654166
Publisher
Lippincott Williams and Wilkins
Year
2000
Tongue
English
Weight
491 KB
Volume
101
Category
Article
ISSN
0009-7322

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The expression of regucalcin, a regulatory protein of Ca(2+) signaling, and its effect on Ca(2+) pump activity in the microsomes (sarcoplasmic reticulum) of rat heart muscle was investigated. The expression of regucalcin mRNA was demonstrated by reverse transcription-polymerase chain reaction (RT-PC