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Responsiveness of hepatocytes to epidermal growth factor, transforming growth factor-beta and norepinephrine during treatment with xenobiotic hepatic tumor promoters

โœ Scribed by Tsai, W.-H.; Michalopoulos, G.K.


Book ID
123392880
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
805 KB
Volume
57
Category
Article
ISSN
0304-3835

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Response to transforming growth factor ฮฑ
โœ G. Hege Thoresen; Tormod K. Guren; Dagny Sandnes; Matthew Peak; Loranne Agius; T ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 254 KB ๐Ÿ‘ 1 views

The epidermal growth factor (EGF) receptor mediates the effects of both EGF and transforming growth factor alpha (TGFalpha). Recent data suggested that EGF acts as a partial agonist/antagonist in hepatocytes, TGFalpha exerting a larger maximal stimulation of DNA synthesis than EGF. To further study