✦ LIBER ✦

Long-term treatment with hepatic tumor promoters inhibits mitogenic responses of hepatocytes to acidic fibroblast growth factor and hepatocyte growth factor

✍ Scribed by Tsai, W.-H.; Zarnegar, R.; Michalopoulos, G.K.

Book ID: 123451113
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 633 KB
Volume: 59
Category: Article
ISSN: 0304-3835
DOI: 10.1016/0304-3835(91)90173-F

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Responsiveness of hepatocytes to epiderm

Responsiveness of hepatocytes to epidermal growth factor, transforming growth factor-beta and norepinephrine during treatment with xenobiotic hepatic tumor promoters

✍ Tsai, W.-H.; Michalopoulos, G.K. 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 805 KB

Response to transforming growth factor α

Response to transforming growth factor α (TGFα) and epidermal growth factor (EGF) in hepatocytes: Lower EGF receptor affinity of TGFα is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater efficacy in stimulation of DNA synthesis

✍ G. Hege Thoresen; Tormod K. Guren; Dagny Sandnes; Matthew Peak; Loranne Agius; T 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

The epidermal growth factor (EGF) receptor mediates the effects of both EGF and transforming growth factor alpha (TGFalpha). Recent data suggested that EGF acts as a partial agonist/antagonist in hepatocytes, TGFalpha exerting a larger maximal stimulation of DNA synthesis than EGF. To further study