Response to rituximab in patients with rheumatoid arthritis in different compartments of the immune system
β Scribed by Maria J. H. Boumans; Rogier M. Thurlings; Danielle M. Gerlag; Koen Vos; Paul P. Tak
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 220 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To study the specific effects of rituximab treatment on the synovium in patients with rheumatoid arthritis (RA) early after initiation of treatment. ## Methods Seventeen RA patients underwent an arthroscopic synovial biopsy procedure directly before and 1 month after rec
## Objective: To determine whether major histocompatibility complex (mhc) polymorphisms are associated with a good or poor response to infliximab therapy in patients with rheumatoid arthritis (ra). ## Methods: Seventy-eight infliximab-treated patients with ra were genotyped for hla-drb1, hla-dqa1
## Abstract ## Objective Treatment of patients with infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, may result in the formation of infliximabβspecific IgG antibodies. This study evaluated the clinical significance of these antibodies in patients with rheumatoid arthr