## Abstract ## Objective To study the quantitative and phenotypic reconstitution of peripheral blood B cells and its relationship to the dynamics of clinical response in patients with rheumatoid arthritis (RA) following B cell depletion with rituximab. ## Methods Twenty‐four patients with active
Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis
✍ Scribed by Jérémie Sellam; Stéphanie Rouanet; Houria Hendel-Chavez; Karim Abbed; Jean Sibilia; Jacques Tebib; Xavier Le Loët; Bernard Combe; Maxime Dougados; Xavier Mariette; Yassine Taoufik
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 235 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Patients with rheumatoid arthritis (RA) in whom the response to anti–tumor necrosis factor (anti‐TNF) therapy is inadequate have several therapeutic options, such as switching to an alternative anti‐TNF agent or initiating B cell–depleting therapy with rituximab (RTX). Alt