Response to Kurien and Scofield: Solubility and bioavailability of curcumin
โ Scribed by Bharat B. Aggarwal
- Book ID
- 116918882
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 61 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0165-6147
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Several authors, in a special issue on curcumin "Curcumin: A Promising Spice for Therapeutics", describe decreased bioavailability of curcumin [1][2][3]. The solution to this problem would be to increase the solubility of curcumin before oral administration. Combined administration of piperine with
Scope: Curcumin, a molecule with pluripharmacological properties, was loaded into solid lipid nanoparticles (SLNs) with a view to improve its oral bioavailability (BA). Methods and results: Curcumin-loaded solid lipid nanoparticles (C-SLNs) with an average particle size of 134.6 nm and a total drug