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Response to hydroxyurea therapy in β-thalassemia

✍ Scribed by Ariel Koren; Carina Levin; Orly Dgany; Tatyan Kransnov; Ronit Elhasid; Lucia Zalman; Haya Palmor; Hannah Tamary

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
93 KB
Volume
83
Category
Article
ISSN
0361-8609

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Hydroxyurea and sodium phenylbutyrate th
Hydroxyurea and sodium phenylbutyrate therapy in thalassemia intermedia
✍ Hoppe, Carolyn; Vichinsky, Elliott; Lewis, Bradley; Foote, Dru; Styles, Lori 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

Hydroxyurea (HU) and sodium phenylbutyrate (SPB) have been shown to increase fetal hemoglobin (Hb F) levels in patients with thalassemia intermedia. The reported effects of these agents in increasing total Hb, however, have been inconsistent and there have been no studies on the combination of these