✦ LIBER ✦

Response to high-dose cisplatin and etoposide in advanced germ cell tumors in children: Results of the Brazilian germ cell tumor study

✍ Scribed by Lopes, Luiz Fernando ;De Camargo, Beatriz ;Dondonis, Miriam ;de Araujo, Rogerio Agenor ;Morinaka, Elizabeth ;,

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 348 KB
Volume: 25
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950250506

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A trial was undertaken to assess the efficacy and toxicity of high‐dose cisplatin and etoposide in children with newly diagnosed advanced malignant germ cell tumors. A total of eleven children and adolescents were treated with courses of high dose cisplatin 30 mg/m^2^/day and etoposide 120 mg/m^2^/day in five day cycles at 21 day intervals. There were eight girls and three boys, aged between 1 and 16 years (median: 120 months). Of nine unresectable tumors, six were in complete remission after three cycles and were completely resected. All patients are alive (median follow‐up 17 months). Preliminary results shows that high dose cisplatin and etoposide is effective in controlling advanced malignant germ cell tumor. © 1995 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

High-risk germ cell tumors in men high r

High-risk germ cell tumors in men high response rate and severe toxicity with cisplatin, vinblastine, bleomycin, and etoposide

✍ Douglas W. Blayney; David A. Goldberg; Lucille A. Leong; Kim A. Margolin; Jerome 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 714 KB

Correlation of serum tumor markers in ad

Correlation of serum tumor markers in advanced germ cell tumors with responses to chemotherapy and surgery

✍ Davor Vugrin; Alan Friedman; Willet F. Whitmore Jr 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 573 KB

Remission rates induced by chemotherapy alone or by combined chemotherapy and surgery were analyzed in relation to specific serum tumor marker abnormalities immediately before treatment in 103 patients with Stage I11 or bulky Stage I1 nonseminomatous germ cell tumors. Complete remission occurred in

Amifostine does not protect against the

Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors : A children's oncology group study

✍ Neyssa Marina; Kay W. Chang; Marcio Malogolowkin; Wendy B. London; A. Lindsay Fr 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

Cisplatin and etoposide salvage therapy

Cisplatin and etoposide salvage therapy and resection of the residual tumor in pretreated germ cell testicular cancer

✍ Giorgio Pizzocaro; Massimo Pasi; Roberto Salvioni; Fulvio Zanoni; Angelo Milani; 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 461 KB 👁 2 views

Cisplatin, etoposide and either bleomyci

Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors : Final analysis of an intergroup trial

✍ Stuart Hinton; Paul J. Catalano; Lawrence H. Einhorn; Craig R. Nichols; E. David 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB 👁 1 views

## Abstract ## BACKGROUND Various staging systems have been proposed for disseminated germ cell neoplasms. The Indiana University staging system was based on clinical and radiographic findings only, whereas the newly created International Germ Cell Cancer Collaborative Group (IGCCCG) staging syste

Sequential trials of cisplatin, vinblast

Sequential trials of cisplatin, vinblastine, and bleomycin and etoposide and cisplatin in disseminated nonseminomatous germ cell tumors of the testis with a good prognosis at a single institution

✍ José R. Germá; Alberto F. Sagarra; Miguel A. Izquierdo; Miguel A. Seguí 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 638 KB