Sequential trials of cisplatin, vinblastine, and bleomycin and etoposide and cisplatin in disseminated nonseminomatous germ cell tumors of the testis with a good prognosis at a single institution
✍ Scribed by José R. Germá; Alberto F. Sagarra; Miguel A. Izquierdo; Miguel A. Seguí
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 638 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND Various staging systems have been proposed for disseminated germ cell neoplasms. The Indiana University staging system was based on clinical and radiographic findings only, whereas the newly created International Germ Cell Cancer Collaborative Group (IGCCCG) staging syste
Most effective treatment regimens for advanced nonseminomatous testis tumors (NSIT) employ vinblastine (V), cisplatin (CDDP), and bleomycin (B) and adjunctive surgery. The toxicity of many of these multidrug programs, primarily from vinblastine-induced myelosuppression has resulted in significant pa