Response of V79 cells to N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) treatment: inhibition of poly(ADP-ribose) and topoisomerase activity
✍ Scribed by Madhumita Roy (Pal); Rita Ghosh; Subrata K. Dey; Sukhendu B. Bhattacharjee
- Book ID
- 113193998
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 383 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0027-5107
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract We examined the action of __N__‐methyl‐__N′__‐nitro‐__N__‐nitrosoguanidine (MNNG) on HeLa cells and compared it with that of cisplatin (CP). MNNG directly killed a substantial number of cells within 1 hour and resulted in strong DNA‐damage as evidenced by Comet measurements. Despite app
The sensitivity to sister chromatid exchange (SCE) induction by N-methyl-nitro-N'-nitrosoguanidine (MNNG) in human, mouse, Chinese hamster, and Syrian hamster normal cell strains and in permanent transformed cell lines of the same species was compared. Exponentially growing or growth-inhibited cultu