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The influence of chronic N-methyl-N′-nitro-N-nitrosoguanidine pre-treatments on mutagenic response and O6-methylguanine-DNA methyltransferase activity in V79 Chinese hamster cells

✍ Scribed by Laura Mariani; Riccardo Bertini; Roberto Fiorio; Piergiovanni Gervasi; Lorenzo Citti

Book ID
114139092
Publisher
Elsevier Science
Year
1988
Weight
265 KB
Volume
208
Category
Article
ISSN
0165-7992

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✍ Sockett, Hilary ;Romac, Stanka ;Hutchinson, Franklin 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 849 KB

DNA base sequence changes induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) mutagenesis have been determined for the Escherichia coli gpt gene stably incorporated in a chromosome of Chinese hamster ovary cells and in the chromosome of both growing and starving E. coli cells, instead of on a pla