RESPONSE OF MOUSE BONE MARROW COLONY FORMING UNITS IN DIFFERENT STAGES OF THE CELL CYCLE TO IN VITRO INCUBATION WITH MITOMYCIN-C
β Scribed by S. K. Lahiri
- Book ID
- 114715014
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 327 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-7722
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π SIMILAR VOLUMES
## Abstract Addition of low concentrations (10 ng/ml) of saponin or Tween 80 to stimulated cultures of normal mouse bone marrow in agar increased the number of granulocyteβmacrophage colonies which developed. Addition of cyclic AMP or dibutyryl cyclic AMP in low concentration (10~β8~ to 10~β10~ M)
It was shown previously that mouse bone marrow cells transformed by simian virus 40 (SV40) show a reversible cell density-dependent phenotypic transition between the nonmacrophage (rapidly growing) and the macrophage (stationary) states; cells in low-density cultures are in the growing phase, expres