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Resolution of rac-ketoprofen esters by enzymatic reactions in organic media

✍ Scribed by Albert Palomer; Marta Cabré; Joan Ginesta; Dr. David Mauleón; Germano Carganico


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
812 KB
Volume
5
Category
Article
ISSN
0899-0042

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Enzymatic resolution of racemic ibuprofe
✍ Masahiro Goto; Sadafumi Noda; Noriho Kamiya; Fumiyuki Nakashio 📂 Article 📅 1996 🏛 Springer Netherlands 🌐 English ⚖ 286 KB

Surfactant-coated lipases have been utilized as a biocatalyst for the resolution of racemic ibuprofen. S-(+)-ibuprofen was selectively transferred to the ester form by Mucor javanicus or Candida rugosa lipase. The enzymatic activity of lipases in organic media was remarkably enhanced by coating with