Resolution of non-protein amino acids vi
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Toshifumi Miyazawa; Hiroe Minowa; Toyoko Miyamoto; Kiwamu Imagawa; Ryoji Yanagih
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Article
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1997
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Elsevier Science
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English
โ 232 KB
In the microbial protease-catalyzed hydrolysis of amino acid esters with the free cx-amino group, the enantioselectivity can be enhanced greatly by employing esters with longer alkyl chains such as the isobutyl ester instead of the conventional methyl ester and by conducting the reaction at low temp