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Resolution of Enantiomers by Non-Conventional Methods

✍ Scribed by Elemer Fogassy; Mihaly Nogradi; Emese Palovics; Jozsef Schindler

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Direct resolution of enantiomers has acquired greater analytical importance. Of various chromatographic techniques, TLC continues to enjoy considerable reputation for the purpose. The present paper deals with an important and yet less explored aspect of TLC i.e. impregnation. Methods of impregnation

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Ibuprofen is one of the most effective and widely used non-steroidal analgesic and anti-inflammatory agent. It is marketed as a racemic mixture though it is known that the pharmacological activity resides in the (S)-()-enantiomer only. Several direct/indirect liquid chromatographic methods involving