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Resistance profile of adefovir dipivoxil (ADV) in immunocompetent and immunocompromised chronic hepatitis B patients after 48 weeks of adefovir dipivoxil therapy

✍ Scribed by C.E. Westland; H. Yang; W.E. Delaney IV; V. Thibault; Y. Benhamou; C.S. Gibbs; M.D. Miller; M. Wulfsohn; M. Sullivan; J. Fry; C.L. Brosgart; S. Xiong


Book ID
118566006
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
162 KB
Volume
38
Category
Article
ISSN
0168-8278

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Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance in treatment-naΓ―ve chronic hepatitis B patients, the association of ADV resistance with previous lamivudine (LAM) resistance is not well understood. We compared the emergence of the ADV-resistant mutations rt