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Resistance of herpes simplex virus type 1 to acyclovir: Thymidine kinase gene mutagenesis study

โœ Scribed by Emilie Frobert; Tadamasa Ooka; Jean-Claude Cortay; Bruno Lina; Danielle Thouvenot; Florence Morfin

Book ID
113457370
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
216 KB
Volume
73
Category
Article
ISSN
0166-3542

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## Abstract We previously isolated an acyclovir (ACV)โ€resistant herpes simplex virus type 1 (HSVโ€1), strain TAR, from a child with Wiskottโ€Aldrich syndrome. An acyclovirโ€sensitive HSVโ€1, strain TAS, had been isolated from the same patient before the isolation of HSVโ€1 TAR. The TK protein of ACVโ€sen