๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

โœ Scribed by Richard T. Eastman; John White; Oliver Hucke; Kohei Yokoyama; Christophe L.M.J. Verlinde; Michael A. Hast; Lorena S. Beese; Michael H. Gelb; Pradipsinh K. Rathod; Wesley C. Van Voorhis


Book ID
113802990
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
313 KB
Volume
152
Category
Article
ISSN
0166-6851

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Effect of substrate binding loop mutatio
โœ Koustav Maity; Tanushree Banerjee; Narayanappa Prabakaran; Namita Surolia; Avadh ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 713 KB

## Abstract Enoyl acyl carrier protein reductase (ENR), which catalyzes the final and rate limiting step of fatty acid elongation, has been validated as a potential drug target. Triclosan is known to be an effective inhibitor for this enzyme. We mutated the substrate binding site residue Ala372 of

Effect of substrate binding loop mutatio
โœ Koustav Maity; Tanushree Banerjee; Narayanappa Prabakaran; Namita Surolia; Avadh ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 104 KB

## Abstract PfENR A372M mutant showing a different conformation of Methionine compared to the Met206 of EcENR by Koustav Maity et al., pp 30โ€“41.