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Residue R216 and Catalytic Efficiency of a Murine Class Alpha Glutathione S -Transferase toward Benzo[ a ]pyrene 7( R ),8( S )-Diol 9( S ),10( R )-Epoxide †,‡

✍ Scribed by Gu, Yijun; Singh, Shivendra V.; Ji, Xinhua


Book ID
127337623
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
511 KB
Volume
39
Category
Article
ISSN
0006-2960

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Exceptional activity of murine glutathio
✍ Jianxia Guo; Su-Shu Pan; Shivendra V. Singh 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB

## Abstract We have shown previously that the alpha class murine glutathione transferase (GST) isoenzyme mGSTA1‐1, unlike other mammalian class alpha GSTs, is highly efficient in catalyzing the glutathione (GSH) conjugation of (7__R__,8__S__)‐dihydroxy‐(9__S__,10__R__)‐epoxy‐7,8,9,10‐tetrahydrobenz