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Residual effects of prolonged cannabis treatment on shuttle-box avoidance in the rat

โœ Scribed by Alexander Stiglick; Mark E. Llewellyn; Harold Kalant


Publisher
Springer
Year
1984
Tongue
English
Weight
419 KB
Volume
84
Category
Article
ISSN
0033-3158

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โœฆ Synopsis


Chronic oral administration of cannabis extract to rats was examined for its residual effects on shuttle-box avoidance learning. In experiment 1 avoidance learning was assessed in rats that had been tested previously on other behavioral tests. Chronic treatment (3 months) facilitated the learning of shuttle-box avoidance in cannabis-treated animals relative to vehicle controls. In experiment 2 very similar results were obtained in naive rats. These and other residual effects of chronic cannabis treatment are similar to the effects of hippocampal lesions.


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