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Rescue of the Friedreich's ataxia knockout mouse by human YAC transgenesis

✍ Scribed by Mark A. Pook; Sahar Al-Mahdawi; Christopher J. Carroll; Mireille Cossée; Hélène Puccio; Lorraine Lawrence; Peter Clark; Margaret B. Lowrie; Jane L. Bradley; Mark J. Cooper; Michel Kœnig; Susan Chamberlain


Book ID
106257481
Publisher
Springer
Year
2001
Tongue
English
Weight
258 KB
Volume
3
Category
Article
ISSN
1364-6745

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Regional localization by in situ hybridi
✍ Elena Raimondi; Antonella Antonelli; Albert J. Driesel; Massimo Pandolfo 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 345 KB

In order to determine the regional localization of the Friedreich's ataxia (FA) gene on chromosome 9, the DNA probe DR47 (D9S5), which detects a restriction fragment length polymorphism (RFLP) in tight linkage with the disease, was hybridized in situ to metaphase chromosomes. Our results enable the