We used compartmented cultures into NGF plus NT3 compartments, while the combinato study the regulation of adult sensory neurite growth tion of BDNF plus NGF resulted in an inhibition of by neurotrophins. We examined the effects of the neuneurite extension compared with NGF alone. We then rotrophins
โฆ LIBER โฆ
Rescue of dorsal root sensory neurons by nerve growth factor and neurotrophin-3, but not brain-derived neurotrophic factor or neurotrophin-4, is dependent on the level of the p75 neurotrophin receptor
โ Scribed by G.L. Barrett; A. Georgiou; K. Reid; P.F. Bartlett; D. Leung
- Book ID
- 117492356
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 855 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0306-4522
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## Abstract We recently isolated mutant PC12 cell clones (PC84 cells) by transfection of PC12 cells with nerve growth factor (NGF) cDNA. These cells secreted active NGF and extended short processes, but proliferated faster than the parental PC12 cells. Because the expression level of p75, a lowโaff