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Requirement of the Prolyl Isomerase Pin1 for the Replication Checkpoint

✍ Scribed by Winkler, K. E.

Book ID
121162245
Publisher
American Association for the Advancement of Science
Year
2000
Tongue
English
Weight
1015 KB
Volume
287
Category
Article
ISSN
0036-8075

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## Abstract Phosphorylation of proteins on serine or threonine residues that immediately precede proline (pSer/Thr‐Pro) is a central signaling mechanism in cell proliferation and transformation. Recent studies indicate that certain pSer/Thr‐Pro motifs in native proteins exist in two completely dist