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The prolyl isomerase Pin1 in breast development and cancer

✍ Scribed by Gerburg Wulf, Akihide Ryo, Yih-Cherng Liou, Kun Ping Lu

Book ID
120701068
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
78 KB
Volume
5
Category
Article
ISSN
1465-5411

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## Abstract Phosphorylation of proteins on serine or threonine residues that immediately precede proline (pSer/Thr‐Pro) is a central signaling mechanism in cell proliferation and transformation. Recent studies indicate that certain pSer/Thr‐Pro motifs in native proteins exist in two completely dist