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Requirement of a partially diploid donor for the chemical induction of mutations in transforming DNA

✍ Scribed by John T. Heard Jr.; Thomas S. Matney


Book ID
113191812
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
433 KB
Volume
69
Category
Article
ISSN
0027-5107

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## Abstract Non‐lethal concentrations of bromodeoxyuridine induce a 2‐ to 5‐fold increase in the specific activity of alkaline phosphatase in HeLa subclone, S3G. Experiments employing 10‐hour pulses of BRdU showed that 48 hours were required before induction commenced, and that maximal induction wa