## Abstract An optimized single‐shot proton double‐quantum (DQ) filter for the quantification of γ‐aminobutyric acid (GABA) levels in human brain is reported. It is demonstrated that creation of DQ coherences following dual‐resonance‐selective refocusing gives a theoretical editing efficiency of 50
✦ LIBER ✦
Reproducibility of prefrontal γ-aminobutyric acid measurements with J-edited spectroscopy
✍ Scribed by Matthew Geramita; Jan Willem van der Veen; Alan S. Barnett; Antonina A. Savostyanova; Jun Shen; Daniel R. Weinberger; Stefano Marenco
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 935 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1662
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The surface-enhanced Raman spectroscopy ( SERS ) of g-aminobutyric acid ( GABA ) adsorbed on silver colloids in H 2 O and D 2 O were recorded and analyzed. When the concentration is greater than 10 03 M , the adsorbed species is the anionic form of the amino acid that interacts with the surface thro