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Repression of BCL2 by the Tumor Suppressor Activity of the Lysyl Oxidase Propeptide Inhibits Transformed Phenotype of Lung and Pancreatic Cancer Cells

✍ Scribed by Wu, M.; Min, C.; Wang, X.; Yu, Z.; Kirsch, K. H.; Trackman, P. C.; Sonenshein, G. E.


Book ID
118199628
Publisher
American Association for Cancer Research
Year
2007
Tongue
English
Weight
388 KB
Volume
67
Category
Article
ISSN
0008-5472

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✍ John J. Grzesiak; Michael Bouvet πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 755 KB

## Abstract The authors have previously demonstrated that Ξ±~2~Ξ²~1~ integrin‐mediated pancreatic cancer cell adhesion to Type I collagen is Mg^2+^‐dependent, inhibited by Ca^2+^, and that this integrin, purified from cell lysates using Type I‐collagen‐sepharose in Mg^2+^, can be eluted with Ca^2+^.