Cyclooxygenase (COX)-2 is one of the rate-limiting enzymes in the conversion of arachidonic acid to prostaglandins and other eicosanoids. Recent studies have shown enhanced expression of COX-2 in cancer cells of several tissues. We investigated the expression of COX-2 and prostaglandin (PG) E 2 prod
β¦ LIBER β¦
Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2
β Scribed by Ying Qiang ZHONG; Zhong Sheng XIA; Yu Ru FU; Zhao Hua ZHU
- Book ID
- 111414488
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2010
- Tongue
- English
- Weight
- 492 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1751-2972
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## Abstract Vitamin C plays a crucial role in the suppression of proliferation of several types of cancer. Overβexpression of cyclooxygenase (COX)β2 and type I insulinβlike growth factor (IGF) receptor are important for proliferation and protection from apoptosis in malignancies. However, its speci