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Repression by oxidative stress of iNOS and cytokine gene induction in macrophages results from AP-1 and NF-κB inhibition mediated by B cell translocation gene-1 activation

✍ Scribed by Il Je Cho; Ae Kyung Lee; Song Jin Lee; Myung Gull Lee; Sang Geon Kim


Book ID
113629682
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
635 KB
Volume
39
Category
Article
ISSN
0891-5849

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Oxidative stress enhances AP-1 and NF-κB
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b 2 -Glycoprotein I (b 2 -GPI), also known as apolipoprotein H, is a plasma glycoprotein with poorly defined gene regulation. The aim of this study was to clarify the role of oxidative stress in b 2 -GPI gene regulation and determine the essential transcription element regulating b 2 -GPI expression