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Reply to the prognostic difference of monoallelic versus biallelic deletion of 13q in chronic lymphocytic leukemia

✍ Scribed by Susan O'Brien

Book ID
112067152
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
422 KB
Volume
118
Category
Article
ISSN
0008-543X

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We used BAC array-based CGH to detect genomic imbalances in 187 CLL cases. Submicroscopic deletions of chromosome 22q11 were observed in 28 cases (15%), and the frequency of these deletions was second only to loss of the 13q14 region, the most common genomic aberration in CLL. Oligonucleotide-based