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Reply to Dvorak and Pavek, Letter to the Editor, regarding “The role of redox-sensitive transcription factors NF-κB and AP-1 in the modulation of Cyp1a1 gene by mercury, lead, and copper”

✍ Scribed by Hesham M. Korashy; Ayman O.S. El-Kadi

Book ID: 113630635
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 119 KB
Volume: 45
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2008.06.001

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## Abstract We have previously shown that Hg^2+^, Pb^2+^, and Cu^2+^, significantly modulate the expression of NAD(P):quinone oxidoreductase 1 (Nqo1) in Hepa 1c1c7 cells through oxidative stress‐dependent mechanisms. In the current study, we examined the role of redox‐sensitive transcription factor