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Comment on “The role of redox-sensitive transcription factors NF-kB and AP-1 in the modulation of the Cyp1A1 gene by mercury, lead, and copper”

✍ Scribed by Zdenek Dvorak; Petr Pavek


Book ID
113630636
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
109 KB
Volume
45
Category
Article
ISSN
0891-5849

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NF-κB and AP-1 are key signaling pathway
✍ Hesham M. Korashy; Ayman O. S. El-Kadi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract We have previously shown that Hg^2+^, Pb^2+^, and Cu^2+^, significantly modulate the expression of NAD(P):quinone oxidoreductase 1 (Nqo1) in Hepa 1c1c7 cells through oxidative stress‐dependent mechanisms. In the current study, we examined the role of redox‐sensitive transcription factor