Replication study of genome-wide associated SNPs with late-onset Alzheimer's disease
β Scribed by L.C. Burns; R.L. Minster; F.Y. Demirci; M.M. Barmada; M. Ganguli; O.L. Lopez; S.T. DeKosky; M.I. Kamboh
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 245 KB
- Volume
- 156
- Category
- Article
- ISSN
- 1552-4841
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The __MAPT__ gene that encodes Tau is located on chromosome 17q21, in a region, which has evolved to form two major haplotypes, H1 and H2. There is strong evidence that the H1 haplotype, and a subβhaplotype (H1C), are overrepresented and associated with increased risk for the sporadic t
## Abstract Lateβonset Alzheimer's disease (LOAD) is a genetically complex neurodegenerative disorder. Currently, only the Ξ΅4 allele of the Apolipoprotein E gene has been identified unequivocally as a genetic susceptibility factor for LOAD. Others remain to be found. In 2002 we observed genomeβwide