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Association studies of 22 candidate SNPs with late-onset Alzheimer's disease

✍ Scribed by Jessica A. Figgins; Ryan L. Minster; F. Yesim Demirci; Steven T. DeKosky; M. Ilyas Kamboh

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
96 KB
Volume
150B
Category
Article
ISSN
1552-4841

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## Abstract The __MAPT__ gene that encodes Tau is located on chromosome 17q21, in a region, which has evolved to form two major haplotypes, H1 and H2. There is strong evidence that the H1 haplotype, and a sub‐haplotype (H1C), are overrepresented and associated with increased risk for the sporadic t