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Replication of a bacterial plasmid and an episome in Escherichia coli

✍ Scribed by Bazaral, Michael G.; Helinski, Donald R.

Book ID
127100125
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
885 KB
Volume
9
Category
Article
ISSN
0006-2960

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Plasmid pTSO118 containing the Escherichia coli origin of replication, oriC, initiated replication simultaneously with the chromosome when temperature-sensitive host cells were synchronized by temperature shifts. Replicating intermediates of the plasmid as well as of the chromosome were isolated fro