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Replication Factors License Exonuclease I in Mismatch Repair

✍ Scribed by Jennifer A Surtees; Eric Alani

Book ID
116753591
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
131 KB
Volume
15
Category
Article
ISSN
1097-2765

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## Abstract The primary role of mismatch repair (MMR) is to maintain genomic stability by removing replication errors from DNA. This repair pathway was originally implicated in human cancer through an association between microsatellite instability in colorectal tumors in hereditary nonpolyposis col