Repetitive mechanical stretching modulates IL-1β induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts
✍ Scribed by Guoguang Yang; Hee-Jeong Im; James H.-C. Wang
- Book ID
- 116507294
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 352 KB
- Volume
- 363
- Category
- Article
- ISSN
- 0378-1119
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Tendon cells receive mechanical signals from the load bearing matrices. The response to mechanical stimulation is crucial for tendon function. However, overloading tendon cells may deteriorate extracellular matrix integrity by activating intrinsic factors such as matrix metalloproteinas
## Abstract The dynamics between inflammatory factors, mechanical stress, and healing factors, in an intra‐articular joint, are very complex after injury. Injury to intra‐articular tissue [anterior cruciate ligament (ACL), synovium] results in hypoxia, accumulation of various pro‐inflammatory facto