The sequence of events leading to a diverse and competent alpha beta T-cell repertoire has been known in outline form for some time. Details continue to be sketched in, however, and some of these suggest previously unsuspected influences on repertoire content.
Repertoire of the αβ T-cell receptor in the intestine
✍ Scribed by Christopher S. J. Probert; Lawrence J. Saubermann; Steven Balk; Richard S. Blumberg
- Book ID
- 111247815
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 260 KB
- Volume
- 215
- Category
- Article
- ISSN
- 0105-2896
No coin nor oath required. For personal study only.
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The selection of developing and mature alpha beta T cells, by intrathymic and extra-thymic ligands expressed on cells of hemopoietic and other origins, has been studied in a variety of systems. These experiments have increased our knowledge of the selection of alpha beta T cells in the thymus, in th