𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Generation of the αβ T-cell repertoire

✍ Scribed by Christophe Benoist; Diane Mathis

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
817 KB
Volume
4
Category
Article
ISSN
0952-7915

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✦ Synopsis

The sequence of events leading to a diverse and competent alpha beta T-cell repertoire has been known in outline form for some time. Details continue to be sketched in, however, and some of these suggest previously unsuspected influences on repertoire content.

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✍ Harald von Boehmer 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 761 KB

The selection of developing and mature alpha beta T cells, by intrathymic and extra-thymic ligands expressed on cells of hemopoietic and other origins, has been studied in a variety of systems. These experiments have increased our knowledge of the selection of alpha beta T cells in the thymus, in th