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Repeated primed in situ labeling: formation and labeling of specific DNA sequences in chromosomes and nuclei

✍ Scribed by Terkelsen, C.; Koch, J.; Kølvraa, S.; Hindkjær, J.; Pedersen, S.; Bolund, L.


Book ID
119984921
Publisher
S. Karger AG
Year
1993
Tongue
French
Weight
642 KB
Volume
63
Category
Article
ISSN
1424-8581

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Primed in situ labeling (PRINS) is a relatively new technology with wide-ranging applications in clinical cytogenetics. Using PRINS, we have identified the chromosomal origin of marker chromosomes in three patients. In the first patient with primary amenorrhea, we were able to confirm the marker chr