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Primed in situ labeling (PRINS): a method for rapid identification and quantification of human chromosomes in both lymphocytes and sperm nuclei

✍ Scribed by Musio, Antonio; Baroli, Paolo; Sbrana, Isabella


Book ID
118164962
Publisher
NRC Research Press
Year
1998
Tongue
English
Weight
237 KB
Volume
41
Category
Article
ISSN
0831-2796

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Primed in situ labeling (PRINS) is a relatively new technology with wide-ranging applications in clinical cytogenetics. Using PRINS, we have identified the chromosomal origin of marker chromosomes in three patients. In the first patient with primary amenorrhea, we were able to confirm the marker chr