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Repeated measurement of spontaneous and clastogen-induced sister-chromatid exchange

✍ Scribed by S. Schwartz; J.A. Astemborski; A.P. Budacz; J.A. Boughman; S.S. Wasserman; M.M. Cohen


Book ID
113251931
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
618 KB
Volume
234
Category
Article
ISSN
0165-1161

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Glutathione (GSH) dissolved in Eagle's MEM and added to cultures of V79-E cells in concentrations between 2.5 X 10 -4 and 10 -3 moles/l for 1 h induces a dose-dependent cell cycle delay, sister chromatid exchanges and clastogenic damage. 7-8% of the metaphases showed endoreduplication at a recovery