Repeated subconvulsant doses of the GABA antagonist drugs picrotoxin (5mg/kg), pentylenetetrazol (PTZ) (30mg/kg), and bicuculline (3.5 mg/kg), were given IP once daily to rats. Picrotoxin produced rapid kindling to full seizures in about 5 days, PTZ produced sporadic myoclonic seizures after 17 days
β¦ LIBER β¦
Repeated Doses of Drugs
β Scribed by GADDUM, J. H.
- Book ID
- 109543553
- Publisher
- Nature Publishing Group
- Year
- 1944
- Tongue
- English
- Weight
- 101 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/153494a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Repeated administration of subconvulsant
β
David J. Nutt; Philip J. Cowen; Celia C. Batts; David G. Grahame-Smith; A. Richa
π
Article
π
1982
π
Springer
π
English
β 377 KB
Repeated administration of subconvulsant
β
Philip J. Cowen; David J. Nutt; Celia C. Batts; A. Richard Green; David J. Heal
π
Article
π
1982
π
Springer
π
English
β 403 KB
Flumazenil infusion or repeated doses
β
G.R. Park; A. Bodenham
π
Article
π
1989
π
John Wiley and Sons
π
English
β 128 KB
Repeated small doses of a neurotoxic org
β
Marcello Lotti; M. K. Johnson
π
Article
π
1980
π
Springer-Verlag
π
English
β 499 KB
The effects of small repeated oral doses of mono-2-cresyl diphenyl phosphate (MOCP, 2.5 mg/kg/day) on hen brain and spinal cord neurotoxic esterase (NTE) were measured. The enzyme levels were depressed to about 40% and 55% of normal respectively and maintained at that level for 8 weeks. No clinical
Effect of lindane at repeated low doses
β
J.M. Tusell; C. SuΓ±ol; E. GelpΓ; E. Rodriguez-FarrΓ©
π
Article
π
1988
π
Elsevier Science
π
English
β 257 KB
Paracetamol plus supplementary doses of
β
H. Quiding; G. Persson; U. AhlstrΓΆm; S. BΓ₯ngens; S. Hellem; G. Johansson; E. JΓΆn
π
Article
π
1982
π
Springer
π
English
β 527 KB