Repeated administration of a dopamine D1 receptor agonist reverses the increased proportions of striatal dopamine D1High and D2High receptors in methamphetamine-sensitized rats
β Scribed by Takahide Shuto; Philip Seeman; Mahomi Kuroiwa; Akinori Nishi
- Book ID
- 109027458
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 257 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0953-816X
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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a KrebsβHEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am