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Reoccurrence of WHV-DNA integration in a described cellular DNA site: Possible link with HCC development in woodchuck

โœ Scribed by E. D'Ugo; R. Bruni; C. Argentini; R. Giuseppetti; A. Cesolini; A. R. Ciccaglione; M. Rapicetta

Book ID
112781440
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
157 KB
Volume
121
Category
Article
ISSN
1432-1335

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The chromosomal sites of woodchuck hepatitis virus (WHV) DNA integration were identified in a woodchuck hepatocellular carcinoma-derived cell line (WH257GE 10) by the in situ hybridization technique using 'H-labelled WHV whole genome (WHV 2) as a probe. The C-banded chromosome spreads from WH257GE 1