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Renal toxicity studies of protein-bound platinum(cis)

✍ Scribed by W.C. Cole; W. Wolf

Book ID
113136263
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
510 KB
Volume
35
Category
Article
ISSN
0009-2797

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A clinical trial was undertaken to improve the therapeutic index of cis-platinum diammine dichloride with a concomitantly administered mannitol induced diuresis. Sixty patients, heavily pretreated, were entered; fifty-one are evaluable. The technique of concomitant osmotic diuresis and CPDD administ