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Prevention of renal toxicity of cis-diamminedichloroplatinum by dithiocarbamates in rats

โœ Scribed by Hideaki, Shimada; Naho, Sugimachi; Takayuki, Funakoshi; Shoji, Kojima

Book ID
122426410
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
368 KB
Volume
66
Category
Article
ISSN
0378-4274

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Comparative effects of diethyldithiocarb
Comparative effects of diethyldithiocarbamate and n-benzyl-d-glucamine dithiocarbamate on cis-diamminedichloroplatinum-induced toxicity in kidney and gastrointestinal tract in rats
โœ Shinji Hidaka; Takayuki Funakoshi; Hideaki Shimada; Michio Tsuruoka; Shoji Kojim ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 701 KB

Sodium diethyldithiocarbamate (DDTC) and sodium N-benzyl-D-glucamine dithiocarbamate (BGD) were compared for their protective effects against cis-diamminedichloroplatinum (DDP)-induced toxicity in kidney and gastrointestinal tract in rats. Rats were injected i.p. with the dithiocarbamates (2.0 mmol