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Renal side effects of lithium: The importance of the serum lithium level

โœ Scribed by Per Vestergaard; Klaus Thomsen


Book ID
104771341
Publisher
Springer
Year
1981
Tongue
English
Weight
143 KB
Volume
72
Category
Article
ISSN
0033-3158

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โœฆ Synopsis


Patients given long-term treatment with lithium often develop an impairment of renal water reabsorption which may lead to clinically significant adverse reactions. A convenient measure of this impairment may be obtained using the ratio of urine volume (V) divided by lithium clearance (CLi). When data from a large group of patients were recalculated, this ratio showed a statistically significant correlation with the serum lithium level. This finding supports the suggestion that patients might advantageously be maintained at lower serum levels than those commonly employed.


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